Abstract

Keywords

Data Availability

No datasets were generated or analysed during the current study.

Abbreviations

  • AA:: Amino acid
  • ADF:: Acid detergent fiber
  • AMP:: Adenosine monophosphate
  • AMPK:: Adenosine monophosphate-activated protein kinase
  • AMPK/PGC1α:: AMPK-peroxisome proliferator-activated receptorγ coactivator 1-α
  • ATIC/GPAT:: IMP cyclohydrolase/glutamine-PRPP amidotransferase
  • ATP5A1:: ATP synthase F1 subunit alpha
  • CAT:: Catalase
  • C/EBPα:: CCAAT/enhancer-binding protein α
  • CF:: Crude fiber
  • CLA:: Conjugated linoleic acid
  • CP:: Crude protein
  • DM:: Dry matter
  • EAA:: Essential amino acids
  • EE:: Ether extract
  • FAA:: Flavor amino acids
  • FABP4:: Fatty acid-binding protein 4
  • FASN:: Fatty acid synthase
  • GADD45a:: Growth arrest and DNA damage
  • GSH-Px:: Glutathione peroxidase
  • HMP:: 2-Hydroxy-4-methylpentanoic acid
  • IBD:: Inflammatory bowel disease
  • IMF:: Intramuscular fat
  • IMP:: Inosine monophosphate
  • LAB:: Lactic acid bacteria
  • MDA:: Malondialdehyde
  • MUFA:: Monounsaturated fatty acids
  • MyHC-I:: Myosin heavy chain-I
  • MyHC-IIa:: Myosin heavy chain-IIa
  • MyHC-IIx:: Myosin heavy chain-IIx
  • MyHC-IIb:: Myosin heavy chain-IIb
  • NDF:: Neutral detergent fiber
  • NEAA:: Nonessential amino acids
  • n-3 PUFA:: n-3 polyunsaturated fatty acids
  • NSP:: Non-starch polysaccharide
  • PI3K-Akt:: Phosphoinositide 3-kinase- protein kinase
  • PPARγ:: Peroxisome proliferator-activated receptor-γ
  • PUFA:: Polyunsaturated fatty acids
  • SCFAs:: Short-chain fatty acids
  • SFA:: Saturated fatty acids
  • SOD:: Superoxide dismutase
  • SREBP1:: Stearoyl-CoA desaturase enzyme 1
  • SSF:: Solid-state fermentation
  • TAG:: Triglycerides
  • T-AOC:: Total superoxide dismutase
  • TCA-SP:: Trichloroacetic acid soluble protein
  • UFA:: Unsaturated fatty acids

References

  1. 1.Chernukha I, Kotenkova E, Pchelkina V, Ilyin N, Utyanov D, Kasimova T, et al. Pork fat and meat.(2023)a balance between consumer expectations and nutrient composition of four pig breeds.Foods.: 690.
    10.3390/foods12040690
    Article|CAS|PubMed|Google Scholar
  2. 2.Lebret B, Čandek-Potokar M. Review.(2022)Pork quality attributes from farm to fork. Part I. Carcass and fresh meat.Animal.: 100402.
    10.1016/j.animal.2021.100402
    Article|CAS|PubMed|Google Scholar
  3. 3.Liu YY, Kong XF, Jiang GL, Tan BE, Deng JP, Yang XJ, et al. Effects of dietary protein/energy ratio on growth performance, carcass trait, meat quality, and plasma metabolites in pigs of different genotypes. J Anim Sci Biotechnol. 2015;6.(2015)org/10.1186/s40104-015-0036-x.: 36.
    10.1186/s40104-015-0036-x
    Article|CAS|PubMed|Google Scholar
  4. 4.Chen GS, Sui YN. Production, performance, slaughter characteristics, and meat quality of Ziwuling wild crossbred pigs. Trop Anim Health Prod. 2018;50(2).(2018)org/10.1007/s11250-017-1441-2.: 365.
    10.1007/s11250-017-1441-2
    Article|CAS|PubMed|Google Scholar
  5. 5.Qi KK, Men XM, Wu J, Xu ZW. Rearing pattern alters porcine myofiber type, fat deposition, associated microbial communities and functional capacity. BMC Microbiol. 2019;19.(2019)org/10.1186/s12866-019-1556-x.: 181.
    10.1186/s12866-019-1556-x
    Article|CAS|PubMed|Google Scholar
  6. 6.Lian X, Shi MY, Lin QL, Liang Y, Zhang LY. Research progress of probiotics and fermented feed effects on pork quality. Food Bioeng. 2024;3(1).(2024)1002/fbe2.12082.: 83.
    10.1002/fbe2.12082
    Article|CAS|PubMed|Google Scholar
  7. 7.Zhang S, Huang YQ, Zheng CB, Wang LY, Zhou YB, Chen WT, et al. Leucine improves the growth performance, carcass traits, and lipid nutritional quality of pork in Shaziling pigs. Meat Sci. 2024;210.(2024)109435. https://doi. org/10. 1016/j.meatsci.: 109435.
    10.1016/j.meatsci.2024.109435
    Article|CAS|PubMed|Google Scholar
  8. 8.Wang LY, Zhang S, Huang YQ, You WJ, Zhou YB, Chen WT, et al. CLA improves the lipo-nutritional quality of pork and regulates the gut microbiota in Heigai pigs. Food Funct. 2022;13(23).(2022)org/10.1039/D2FO02549C.: 12093.
    10.1039/D2FO02549C
    Article|CAS|PubMed|Google Scholar
  9. 9.Liu YY, Peng YL, Chen C, Ren HB, Zhu J, Deng Y, et al. Flavonoids from mulberry leaves inhibit fat production and improve fatty acid distribution in adipose tissue in finishing pigs. Anim Nutr. 2024;16.(2024)11.003.: 147.
    10.1016/j.aninu.2023.11.003
    Article|CAS|PubMed|Google Scholar
  10. 10.Guo ZY, Chen XL, Huang ZQ, Chen DW, Li MZ, Yu B, et al. Dihydromyricetin improves meat quality and promotes skeletal muscle fiber type transformations via AMPK signaling in growing-finishing pigs. Food Funct. 2022;13(6).(2022)org/10.1039/d1fo03391c.: 3649.
    10.1039/d1fo03391c
    Article|CAS|PubMed|Google Scholar
  11. 11.Sun HX, Chen D, Cai HY, Chang WH, Wang ZD, Liu GH, et al. Effects of fermenting the plant fraction of a complete feed on the growth performance, nutrient utilization, antioxidant functions, meat quality, and intestinal microbiota of broilers. Animals. 2022;12(20).(2022)org/10.3390/ani12202870.: 2870.
    10.3390/ani12202870
    Article|CAS|PubMed|Google Scholar
  12. 12.Wang C, Su WF, Zhang Y, Hao LH, Wang FQ, Lu ZQ, et al. Solid-state fermentation of distilled dried grain with solubles with probiotics for degrading lignocellulose and upgrading nutrient utilization. AMB Express. 2018;8(1).(2018)org/10.1186/s13568-018-0715-z.: 188.
    10.1186/s13568-018-0715-z
    Article|CAS|PubMed|Google Scholar
  13. 13.Liu P, Zhao J, Guo P, Lu W, Geng Z, Levesque CL, et al. Dietary corn bran fermented byBacillus subtilisMA139 decreased gut cellulolytic bacteria and microbiota diversity in finishing pigs. Front Cell Infect Microbiol. 2017;7.(2017)526. https://doi. org/10.3389/fcimb.: 526.
    10.3389/fcimb.2017.00526
    Article|CAS|PubMed|Google Scholar
  14. 14.Yang YZ, Yan GH, Meng XH, Wang X, Zhao ZQ, Zhou SG, et al. Effects ofLactobacillus plantarumandPediococcus acidilacticico-fermented feed on growth performance and gut microbiota of nursery pigs. Front Vet Sci. 2022;9.(2022)1076906. https://doi. org/10.3389/fvets.: 1076906.
    10.3389/fvets.2022.1076906
    Article|CAS|PubMed|Google Scholar
  15. 15.Xu F, Wu HZ, Xie JJ, Zeng T, Hao LJ, Xu WW, et al. The effects of fermented feed on the growth performance, antioxidant activity, immune function, intestinal digestive enzyme activity, morphology, and microflora of yellow-feather chickens. Animals. 2023;13(22).(2023)org/10.3390/ani13223545.: 3545.
    10.3390/ani13223545
    Article|CAS|PubMed|Google Scholar
  16. 16.Zhu JJ, Gao MX, Zhang RL, Sun ZJ, Wang CM, Yang FF, et al. Effects of soybean meal fermented byL. plantarum,B. subtilisandS. cerevisieaeon growth, immune function and intestinal morphology in weaned piglets. Microb Cell Fact. 2017;16(1).(2017)org/10.1186/s12934-017-0809-3.: 191.
    10.1186/s12934-017-0809-3
    Article|CAS|PubMed|Google Scholar
  17. 17.Liu SQ, Du M, Tu YA, You WJ, Chen WT, Liu GL, et al. Fermented mixed feed alters growth performance, carcass traits, meat quality and muscle fatty acid and amino acid profiles in finishing pigs. Anim Nutr. 2023;12.(2023)09.003.: 87.
    10.1016/j.aninu.2022.09.003
    Article|CAS|PubMed|Google Scholar
  18. 18.Rahman M, Bora JR, Sarma AK, Roychoudhury R, Borgohain A. Effect of deep litter housing and fermented feed on carcass characteristics and meat quality of crossbred Hampshire pigs. Vet World. 2015;8(7).(2015)881–7. https://doi. org/10.14202/vetworld.: 881.
    10.14202/vetworld.2015.881-887
    Article|CAS|PubMed|Google Scholar
  19. 19.Tian ZM, Deng D, Cui YY, Chen WD, Yu M, Ma XY. Diet supplemented with fermented okara improved growth performance, meat quality, and amino acid profiles in growing pigs. Food Sci Nutr. 2020;8(10).(2020)1002/fsn3.1857.: 5650.
    10.1002/fsn3.1857
    Article|CAS|PubMed|Google Scholar
  20. 20.Zheng Z, Liu ZQ, Li N, Mu SQ, Liang SY, Liu ZH, et al. Effects of fermented bamboo powder on growth performance, apparent digestibility, carcass traits, and meat quality in growing-finishing pigs. Livest Sci. 2023;277.(2023)105358. https://doi. org/10. 1016/j.livsci.: 105358.
    Article|CAS|PubMed|Google Scholar
  21. 21.Qiu YQ, Li KB, Zhao XC, Liu SL, Wang L, Yang XF, et al. Fermented feed modulates meat quality and promotes the growth of longissimus thoracis of late-finishing pigs. Animals. 2020;10(9).(2020)org/10.3390/ani10091682.: 1682.
    10.3390/ani10091682
    Article|CAS|PubMed|Google Scholar
  22. 22.Chu GM, Park BK. Effects of fermented carrot by-product diets on growth performances, carcass characteristics and meat quality in fattening pigs. Acta Agr Scand, A Anim Sci. 2023;72(1–2).(2023)40–8. https://doi. org/10.1080/09064702.: 40.
    Article|CAS|PubMed|Google Scholar
  23. 23.Ding XQ, Li HY, Wen ZW, Hou Y, Wang GL, Fan JH, et al. Effects of fermented tea residue on fattening performance, meat quality, digestive performance, serum antioxidant capacity, and intestinal morphology in fatteners. Animals. 2020;10(2).(2020)org/10.3390/ani10020185.: 185.
    10.3390/ani10020185
    Article|CAS|PubMed|Google Scholar
  24. 24.Hao LH, Su WF, Zhang Y, Wang C, Xu BC, Jiang ZP, et al. Effects of supplementing with fermented mixed feed on the performance and meat quality in finishing pigs. Anim Feed Sci Technol. 2020.https.(2020)//doi. org/10. 1016/j.anifeedsci.
    10.1016/j.anifeedsci.2020.114501
    Article|CAS|PubMed|Google Scholar
  25. 25.Lu JF, Han QC, Wang SY, Wang ZL, Li X, Hu JH, et al. Effect of fermented corn–soybean meal on carcass and meat quality of grower-finisher pigs. J Anim Physiol Anim Nutr. 2020;105(4).(2020)1111/jpn.13444.: 693.
    10.1111/jpn.13444
    Article|CAS|PubMed|Google Scholar
  26. 26.Jiang HJ, Azad MAK, Zhu Q, Ni HJ, Kong XF. Fermented cassava residue meal improves meat quality by regulating muscle fiber and enhancing lipid metabolism in Huanjiang mini-pigs. Animals. 2025;15(2).(2025)org/10.3390/ani15020177.: 177.
    10.3390/ani15020177
    Article|CAS|PubMed|Google Scholar
  27. 27.Zhang Y, Wang C, Su WF, Jiang ZP, He H, Gong T, et al. Co-fermented yellow wine lees byBacillus subtilisandEnterococcus faeciumregulates growth performance and gut microbiota in finishing pigs. Front Microbiol. 2022;13.(2022)1003498. https://doi. org/10.3389/fmicb.: 1003498.
    10.3389/fmicb.2022.1003498
    Article|CAS|PubMed|Google Scholar
  28. 28.Ahmed ST, Mun HS, Islam MM, Ko SY, Yang CJ. Effects of dietary natural and fermented herb combination on growth performance, carcass traits and meat quality in grower-finisher pigs. Meat Sci. 2016;122.(2016)7–15. https://doi. org/10. 1016/j.meatsci.: 7.
    10.1016/j.meatsci.2016.07.016
    Article|CAS|PubMed|Google Scholar
  29. 29.Lei XJ, Yun HM, Kim IH. Effects of dietary supplementation of natural and fermented herbs on growth performance, nutrient digestibility, blood parameters, meat quality and fatty acid composition in growing-finishing pigs. Ital J Anim Sci. 2018;17(4).(2018)984–93. https://doi. org/10.1080/1828051x.: 984.
    10.1080/1828051x.2018.1429955
    Article|CAS|PubMed|Google Scholar
  30. 30.Xu CH, Xiong PW, Song WJ, Song QL, Hu Y, Song TX, et al. Effects of fermented navel orange pulp on growth performance, carcass characteristics, meat quality, meat nutritional value, and serum biochemical indicators of finishing Tibetan pigs. Foods. 2024;13(12).(2024)org/10.3390/foods13121910.: 1910.
    10.3390/foods13121910
    Article|CAS|PubMed|Google Scholar
  31. 31.Xu X, Li LM, Li B, Guo WJ, Ding XL, Xu FZ. Effect of fermented biogas residue on growth performance, serum biochemical parameters, and meat quality in pigs. Asian-Australas J Anim Sci. 2017;30(10).(2017)16.0777.: 1464.
    10.5713/ajas.16.0777
    Article|CAS|PubMed|Google Scholar
  32. 32.Hati S, Patel M, Mishra BK, Das S. Short-chain fatty acid and vitamin production potentials ofLactobacillusisolated from fermented foods of Khasi Tribes, Meghalaya. India Ann Microbiol. 2019;69(11).(2019)org/10.1007/s13213-019-01500-8.: 1191.
    10.1007/s13213-019-01500-8
    Article|CAS|PubMed|Google Scholar
  33. 33.Li SY, Zhao YJ, Zhang L, Zhang X, Huang L, Li D, et al. Antioxidant activity ofLactobacillus plantarumstrains isolated from traditional Chinese fermented foods. Food Chem. 2012;135(3).(2012)1914–9. https://doi. org/10. 1016/j.foodchem.: 1914.
    10.1016/j.foodchem.2012.06.048
    Article|CAS|PubMed|Google Scholar
  34. 34.Ding WR, Wang LN, Zhang JA, Ke WC, Zhou JW, Zhu JX, et al. Characterization of antioxidant properties of lactic acid bacteria isolated from spontaneously fermented yak milk in the Tibetan Plateau. J Funct Foods. 2017;35.(2017)481–8. https://doi. org/10. 1016/j.jff.: 481.
    10.1016/j.jff.2017.06.008
    Article|CAS|PubMed|Google Scholar
  35. 35.Garbacz K. Anticancer activity of lactic acid bacteria. Semin Cancer Biol. 2022;86(Pt 3).(2022)12.013.: 356.
    10.1016/j.semcancer.2021.12.013
    Article|CAS|PubMed|Google Scholar
  36. 36.Li FH, Ding ZT, Adesogan AT, Ke WC, Jiang Y, Bai J, et al. Effects of class IIa bacteriocin-producingLactobacillusspecies on fermentation quality and aerobic stability of alfalfa silage. Animals. 2020;10(9).(2020)org/10.3390/ani10091575.: 1575.
    10.3390/ani10091575
    Article|CAS|PubMed|Google Scholar
  37. 37.Londero A, León Peláez MA, Diosma G, De Antoni GL, Abraham AG, Garrote GL. Fermented whey as poultry feed additive to prevent fungal contamination. J Sci Food Agric. 2014;94(15).(2014)1002/jsfa.6669.: 3189.
    10.1002/jsfa.6669
    Article|CAS|PubMed|Google Scholar
  38. 38.Qian JY, Wang YZ, Hu ZJ, Shi TQ, Wang YT, Ye C, et al.Bacillussp. as a microbial cell factory.(2023)advancements and future prospects.Biotechnol Adv.: 108278.
    10.1016/j.biotechadv.2023.108278
    Article|CAS|PubMed|Google Scholar
  39. 39.Xu RP, Tian T, Hu B, Zhang ZQ, Liu J, Yu DH, et al. Effect of solid-state fermentation withBacillus pumiluson the nutritional value, anti-nutritional factors and antioxidant activity of faba bean (Vicia fabaL.) meal. Lwt. 2023;185.(2023)115117. https://doi. org/10. 1016/j.lwt.: 115117.
    10.1016/j.lwt.2023.115117
    Article|CAS|PubMed|Google Scholar
  40. 40.Zhang MM, Huang YW, Zhao HC, Wang TF, Xie CQ, Zhang DY, et al. Solid-state fermentation ofMoringa oleiferaleaf meal usingBacillus pumilusCICC 10440. J Chem Technol Biotechnol. 2017;92(8).(2017)1002/jctb.5203.: 2083.
    10.1002/jctb.5203
    Article|CAS|PubMed|Google Scholar
  41. 41.Liu SQ, Cai PR, You WJ, Yang MS, Tu YA, Zhou YB, et al. Enhancement of gut barrier integrity by a Bacillus subtilis secreted metabolite through the GADD45A‐Wnt/β‐catenin pathway. Imeta. 2025;4(2).(2025)1002/imt2.70005.
    10.1002/imt2.70005
    Article|CAS|PubMed|Google Scholar
  42. 42.Chuang WY, Lin WC, Hsieh YC, Huang CM, Chang SC, Lee TT. Evaluation of the combined use ofSaccharomyces cerevisiaeandAspergillus oryzaewith phytase fermentation products on growth, inflammatory, and intestinal morphology in broilers. Animals. 2019;9(12).(2019)org/10.3390/ani9121051.: 1051.
    10.3390/ani9121051
    Article|CAS|PubMed|Google Scholar
  43. 43.Rai AK, Pandey A, Sahoo D. Biotechnological potential of yeasts in functional food industry. Trends Food Sci Tech. 2019;83.(2019)11.016.: 129.
    10.1016/j.tifs.2018.11.016
    Article|CAS|PubMed|Google Scholar
  44. 44.Rai AK, Kumari R, Sanjukta S, Sahoo D. Production of bioactive protein hydrolysate using the yeasts isolated from soft chhurpi. Bioresour Technol. 2016;219.(2016)239–45. https://doi. org/10. 1016/j.biortech.: 239.
    10.1016/j.biortech.2016.07.129
    Article|CAS|PubMed|Google Scholar
  45. 45.Aktar J, Islam KMS, Chowdhury R, Debi MR, Emon AI. Effect of baker’s yeast fermented moist feed on the growth and bone mineralization in broiler. J Adv Vet Anim Res. 2024;11(1).(2024)78–84. https://doi. org/10.5455/javar.: 78.
    10.5455/javar.2024.k750
    Article|CAS|PubMed|Google Scholar
  46. 46.Azrinnahar M, Islam N, Shuvo AAS, Kabir AKMA, Islam KMS. Effect of feeding fermented (Saccharomyces cerevisiae) de-oiled rice bran in broiler growth and bone mineralization. J Saudi Soc Agric Sci. 2021;20(7).(2021)476–81. https://doi. org/10. 1016/j.jssas.: 476.
    10.1016/j.jssas.2021.05.006
    Article|CAS|PubMed|Google Scholar
  47. 47.Hammod A. Effect of corn fermented bySaccharomyces cerevisiaein diets on production performance of broiler chicks. J Pure Appl Microbiol. 2019;13(2).(2019)2.40.: 1025.
    10.22207/jpam.13.2.40
    Article|CAS|PubMed|Google Scholar
  48. 48.Nocek JE, Holt MG, Oppy J. Effects of supplementation with yeast culture and enzymatically hydrolyzed yeast on performance of early lactation dairy cattle. J Dairy Sci. 2011;94(8).(2011)4046–56. https://doi. org/10.3168/jds.: 4046.
    10.3168/jds.2011-4277
    Article|CAS|PubMed|Google Scholar
  49. 49.Vailati-Riboni M, Coleman DN, Lopreiato V, Alharthi A, Bucktrout RE, Abdel-Hamied E, et al. Feeding aSaccharomyces cerevisiaefermentation product improves udder health and immune response to aStreptococcus uberismastitis challenge in mid-lactation dairy cows. J Anim Sci Biotechnol. 2021;12.(2021)org/10.1186/s40104-021-00560-8.: 62.
    10.1186/s40104-021-00560-8
    Article|CAS|PubMed|Google Scholar
  50. 50.Lim DH, Han MH, Ki KS, Kim TI, Park SM, Kim DH, et al. Changes in milk production and blood metabolism of lactating dairy cows fedSaccharomyces cerevisiaeculture fluid under heat stress. J Anim Sci Technol. 2021;63(6).(2021)1433–42. https://doi. org/10.5187/jast.: 1433.
    10.5187/jast.2021.e114
    Article|CAS|PubMed|Google Scholar
  51. 51.Espitia-Hernandez P, Ruelas-Chacon X, Chavez-Gonzalez ML, Ascacio-Valdes JA, Flores-Naveda A, Sepulveda-Torre L. Solid-state fermentation of sorghum byAspergillus oryzaeandAspergillus niger.(2022)effects on tannin content, phenolic profile, and antioxidant activity.Foods.: 3121.
    10.3390/foods11193121
    Article|CAS|PubMed|Google Scholar
  52. 52.Colla LM, Ficanha AM, Rizzardi J, Bertolin TE, Reinehr CO, Costa JAV. Production and characterization of lipases by two new isolates ofAspergillusthrough solid-state and submerged fermentation. BioMed Res Int. 2015;2015.(2015)725959. https://doi. org/10.1155/.: 725959.
    10.1155/2015/725959
    Article|CAS|PubMed|Google Scholar
  53. 53.Falony G, Armas JC, Mendoza JCD, Hernandez JLM. Production of extracellular lipase from Aspergillus niger by solid-state fermentation. Food Technol Biotech. 2006;44(4).(2006)235–40.: 235.
    Article|CAS|PubMed|Google Scholar
  54. 54.Lima LGR, Gonçalves MMM, Couri S, Melo VF, Sant’Ana GCF, Costa ACAD. Lipase production byAspergillus nigerC by submerged fermentation. Braz Arch Biol Technol. 2019.https.(2019)//doi. org/10.1590/1678-4324-.
    10.1590/1678-4324-2019180113
    Article|CAS|PubMed|Google Scholar
  55. 55.Yang LJ, Zeng XF, Qiao SY. Advances in research on solid-state fermented feed and its utilization.(2021)The pioneer of private customization for intestinal microorganisms.Anim Nutr.: 905.
    10.1016/j.aninu.2021.06.002
    Article|CAS|PubMed|Google Scholar
  56. 56.Couto SR, Sanromán MÁ. Application of solid-state fermentation to food industry—a review. J Food Eng. 2006;76(3).(2006)291–302.: 291.
    10.1016/j.jfoodeng.2005.05.022
    Article|CAS|PubMed|Google Scholar
  57. 57.Sugiharto S, Ranjitkar S. Recent advances in fermented feeds towards improved broiler chicken performance, gastrointestinal tract microecology and immune responses.(2019)a review.Anim Nutr.: 1.
    10.1016/j.aninu.2018.11.001
    Article|CAS|PubMed|Google Scholar
  58. 58.Ranjan A, Sahu NP, Deo AD, Kumar S. Solid state fermentation of de-oiled rice bran.(2019)effect on in vitro protein digestibility, fatty acid profile and anti-nutritional factors.Food Res Int.: 1.
    10.1016/j.foodres.2019.01.054
    Article|CAS|PubMed|Google Scholar
  59. 59.Su WF, Jiang ZP, Wang C, Zhang Y, Gong T, Wang FQ, et al. Co-fermented defatted rice bran alters gut microbiota and improves growth performance, antioxidant capacity, immune status and intestinal permeability of finishing pigs. Anim Nutr. 2022;11.(2022)413–24. https://doi. org/10. 1016/j.aninu.: 413.
    10.1016/j.aninu.2022.07.008
    Article|CAS|PubMed|Google Scholar
  60. 60.de Castro RJS, Ohara A, Nishide TG, Bagagli MP, Gonçalves Dias FF, Sato HH. A versatile system based on substrate formulation using agroindustrial wastes for protease production byAspergillus nigerunder solid state fermentation. Biocatal Agric Biotechnol. 2015;4(4).(2015)678–84. https://doi. org/10. 1016/j.bcab.: 678.
    10.1016/j.bcab.2015.08.010
    Article|CAS|PubMed|Google Scholar
  61. 61.Cerda A, El-Bakry M, Gea T, Sánchez A. Long term enhanced solid-state fermentation.(2016)inoculation strategies for amylase production from soy and bread wastes byThermomycessp. in a sequential batch operation.J Environ Chem Eng.: 2394.
    10.1016/j.jece.2016.04.022
    Article|CAS|PubMed|Google Scholar
  62. 62.Qureshi AS, Khushk I, Ali CH, Chisti Y, Ahmad A, Majeed H. Coproduction of protease and amylase by thermophilicBacillussp. BBXS-2 using open solid-state fermentation of lignocellulosic biomass. Biocatal Agric Biotechnol. 2016;8.(2016)146–51. https://doi. org/10. 1016/j.bcab.: 146.
    10.1016/j.bcab.2016.09.006
    Article|CAS|PubMed|Google Scholar
  63. 63.Ferrarezi AL, Hideyuki Kobe Ohe T, Borges JP, Brito RR, Siqueira MR, Vendramini PH, et al. Production and characterization of lipases and immobilization of whole cell of the thermophilicThermomucor indicae seudaticaeN31 for transesterification reaction. J Mol Catal B-Enzym. 2014;107.(2014)106–13. https://doi. org/10. 1016/j.molcatb.: 106.
    10.1016/j.molcatb.2014.05.012
    Article|CAS|PubMed|Google Scholar
  64. 64.Pandey AK, Edgard G, Negi S. Optimization of concomitant production of cellulase and xylanase fromRhizopus oryzaeSN5 through EVOP-factorial design technique and application in Sorghum Stover based bioethanol production. Renew Energy. 2016;98.(2016)51–6. https://doi. org/10. 1016/j.renene.: 51.
    10.1016/j.renene.2016.05.071
    Article|CAS|PubMed|Google Scholar
  65. 65.Yang LJ, Yang ZB, Yang WR, Li HR, Zhang CY, Jiang SZ, et al. Conventional solid fermentation alters mycotoxin contents and microbial diversity analyzed by high-throughput sequencing of aFusariummycotoxin-contaminated diet. Can J Anim Sci. 2018;98(2).(2018)org/10.1139/cjas-2017-0093.: 354.
    10.1139/cjas-2017-0093
    Article|CAS|PubMed|Google Scholar
  66. 66.Cullen JT, Lawlor PG, Cormican P, Gardiner GE. Microbial quality of liquid feed for pigs and its impact on the porcine gut microbiome. Animals. 2021;11(10).(2021)org/10.3390/ani11102983.: 2983.
    10.3390/ani11102983
    Article|CAS|PubMed|Google Scholar
  67. 67.Missotten JAM, Michiels J, Ovyn A, De Smet S, Dierick NA. Fermented liquid feed for pigs. Arch Anim Nutr. 2010;64(6).(2010)437–66. https://doi. org/10.1080/1745039x.: 437.
    10.1080/1745039x.2010.512725
    Article|CAS|PubMed|Google Scholar
  68. 68.Lawlor PG, Lynach PB, Gardiner GE, Caffrey PJ, O’Doherty JV. Effect of liquid feeding weaned pigs on growth performance to harvest. J Anim Sci. 2002;80(7).(2002)1725–35. https://doi. org/10.2527/.: 1725.
    10.2527/2002.8071725x
    Article|CAS|PubMed|Google Scholar
  69. 69.Missotten JA, Michiels J, Degroote J, De Smet S. Fermented liquid feed for pigs.(2015)an ancient technique for the future.J Anim Sci Biotechnol.: 4.
    Article|CAS|PubMed|Google Scholar
  70. 70.Plumed-Ferrer C, von Wright A. Antimicrobial activity of weak acids in liquid feed fermentations, and its effects on yeasts and lactic acid bacteria. J Sci Food Agric. 2011;91(6).(2011)1002/jsfa.4278.: 1032.
    10.1002/jsfa.4278
    Article|CAS|PubMed|Google Scholar
  71. 71.Canibe N, Jensen BB. Fermented and nonfermented liquid feed to growing pigs.(2003)effect on aspects of gastrointestinal ecology and growth performance.J Anim Sci.: 2019.
    10.2527/2003.8182019x
    Article|CAS|PubMed|Google Scholar
  72. 72.O’ Meara FM, Gardiner GE, O’ Doherty JV, Clarke D, Cummins W, Lawlor PG. Effect of wet/dry, fresh liquid, fermented whole diet liquid, and fermented cereal liquid feeding on feed microbial quality and growth in grow-finisher pigs. J Anim Sci. 2020;98(6).(2020)org/10.1093/jas/skaa166.: 1.
    10.1093/jas/skaa166
    Article|CAS|PubMed|Google Scholar
  73. 73.Canibe N, Hojberg O, Badsberg JH, Jensen BB. Effect of feeding fermented liquid feed and fermented grain on gastrointestinal ecology and growth performance in piglets. J Anim Sci. 2007;85(11).(2007)2527/jas.2006-744.: 2959.
    10.2527/jas.2006-744
    Article|CAS|PubMed|Google Scholar
  74. 74.Moran CA, Scholten RH, Tricarico JM, Brooks PH, Verstegen MW. Fermentation of wheat.(2006)effects of backslopping different proportions of pre-fermented wheat on the microbial and chemical composition.Arch Anim Nutr.: 158.
    10.1080/17450390600562700
    Article|CAS|PubMed|Google Scholar
  75. 75.Scholten RHJ, van der Peet-Schwering CMC, den Hartog LA, Balk M, Schrama JW, Verstegen M W. Fermented wheat in liquid diets.(2002)Effects on gastrointestinal characteristics in weanling piglets.J Anim Sci.: 1179.
    Article|CAS|PubMed|Google Scholar
  76. 76.Zhang AR, Yang YY, Li Y, Zheng YF, Wang HM, Cui HX, et al. Effects of wheat-based fermented liquid feed on growth performance, nutrient digestibility, gut microbiota, intestinal morphology, and barrier function in grower-finisher pigs. J Anim Sci. 2024.https.(2024)org/10.1093/jas/skae229.
    10.1093/jas/skae229
    Article|CAS|PubMed|Google Scholar
  77. 77.Plumed-Ferrer C, Llopis M, Hyvönen P, Wright AV. Characterization of the microbial community and its changes in liquid piglet feed formulations. J Sci Food Agric. 2004;84(11).(2004)1002/jsfa.1818.: 1315.
    10.1002/jsfa.1818
    Article|CAS|PubMed|Google Scholar
  78. 78.Engberg RM, Hammershoj M, Johansen NF, Abousekken MS, Steenfeldt S, Jensen BB. Fermented feed for laying hens.(2009)effects on egg production, egg quality, plumage condition and composition and activity of the intestinal microflora.Br Poult Sci.: 228.
    10.1080/00071660902736722
    Article|CAS|PubMed|Google Scholar
  79. 79.Missotten JA, Michiels J, Dierick N, Ovyn A, Akbarian A, De Smet S. Effect of fermented moist feed on performance, gut bacteria and gut histo-morphology in broilers. Br Poult Sci. 2013;54(5).(2013)627–34. https://doi. org/10.1080/00071668.: 627.
    10.1080/00071668.2013.811718
    Article|CAS|PubMed|Google Scholar
  80. 80.Xin HL, Wang MY, Xia Z, Yu B, He J, Yu J, et al. Fermented diet liquid feeding improves growth performance and intestinal function of pigs. Animals. 2021;11(5).(2021)org/10.3390/ani11051452.: 1452.
    10.3390/ani11051452
    Article|CAS|PubMed|Google Scholar
  81. 81.Shuai CY, Chen DW, Yu B, Luo YH, Zheng P, Huang ZQ, et al. Effect of fermented rapeseed meal on growth performance, nutrient digestibility, and intestinal health in growing pigs. Anim Nutr. 2023;15.(2023)420–9. https://doi. org/10. 1016/j.aninu.: 420.
    10.1016/j.aninu.2023.06.011
    Article|CAS|PubMed|Google Scholar
  82. 82.Tie Y, Li L, Liu J, Liu CL, Fu JJ, Xiao XJ, et al. Two-step biological approach for treatment of rapeseed meal. J Food Sci. 2020;85(2).(2020)1111/1750-3841.15011.: 340.
    10.1111/1750-3841.15011
    Article|CAS|PubMed|Google Scholar
  83. 83.Zhu Xf, Wang LY, Zhang Z, Ding LR, Hang SQ. Combination of fiber-degrading enzymatic hydrolysis and lactobacilli fermentation enhances utilization of fiber and protein in rapeseed meal as revealed in simulated pig digestion and fermentation in vitro. Anim Feed Sci Tech. 2021;278.https.(2021)//doi. org/10. 1016/j.anifeedsci.
    Article|CAS|PubMed|Google Scholar
  84. 84.Hu YQ, He YY, Gao S, Liao ZQ, Lai T, Zhou HM, et al. The effect of a diet based on rice straw co-fermented with probiotics and enzymes versus a fresh corn stover-based diet on the rumen bacterial community and metabolites of beef cattle. Sci Rep. 2020;10.(2020)org/10.1038/s41598-020-67716-w.: 10721.
    Article|CAS|PubMed|Google Scholar
  85. 85.Lin BS, Yan JB, Zhong ZL, Zheng XT. A study on the preparation of microbial and nonstarch polysaccharide enzyme synergistic fermented maize cob feed and its feeding efficiency in finishing pigs. BioMed Res Int. 2020;2020.(2020)8839148. https://doi. org/10.1155/.: 8839148.
    10.1155/2020/8839148
    Article|CAS|PubMed|Google Scholar
  86. 86.Sebothoma P, Hlatini VA, Ncobela CN, Thomas RS, Chimonyo M. Effect of liquid-fermented potato hash, with or without exogenous enzymes, on carcass characteristics of growing pigs. S Afr J Anim Sci. 2024;53(5).(2024)v53i5.07.: 678.
    10.4314/sajas.v53i5.07
    Article|CAS|PubMed|Google Scholar
  87. 87.Liu Y, Liu Y, Cao YH, Wang CL. Pretreatment of palm kernel cake by enzyme-bacteria and its effects on growth performance in broilers. Animals. 2025;15(2).(2025)org/10.3390/ani15020116.: 116.
    10.3390/ani15020116
    Article|CAS|PubMed|Google Scholar
  88. 88.Ji MT, Rong XY, Wu YF, Li HN, Zhao XL, Zhao Y, et al. Effects of fermented liquid feed with compound probiotics on growth performance, meat quality, and fecal microbiota of growing pigs. Animals. 2025;15(5).(2025)org/10.3390/ani15050733.: 733.
    10.3390/ani15050733
    Article|CAS|PubMed|Google Scholar
  89. 89.Xie KH, Dai YQ, Zhang AR, Yu B, Luo YH, Li H, et al. Effects of fermented soybean meal on growth performance, meat quality, and antioxidant capacity in finishing pigs. J Funct Foods. 2022;94.(2022)105128. https://doi. org/10. 1016/j.jff.: 105128.
    10.1016/j.jff.2022.105128
    Article|CAS|PubMed|Google Scholar
  90. 90.Lu JF, Zhang XY, Liu YH, Cao HG, Han QC, Xie BC, et al. Effect of fermented corn-soybean meal on serum immunity, the expression of genes related to gut immunity, gut microbiota, and bacterial metabolites in grower-finisher pigs. Front Microbiol. 2019.https.(2019)//doi. org/10.3389/fmicb.
    10.3389/fmicb.2019.02620
    Article|CAS|PubMed|Google Scholar
  91. 91.Shi CY, He J, Yu J, Yu B, Mao XB, Zheng P, et al. Physicochemical properties analysis and secretome ofAspergillus nigerin fermented rapeseed meal. PLoS ONE. 2016;11(4).(2016)pone.0153230.
    10.1371/journal.pone.0153230
    Article|CAS|PubMed|Google Scholar
  92. 92.Sun H, Qian ZC, Wu YF, Tang JW, Shen Q, Li JH, et al. Effects of fermented broccoli stem and leaf residue on growth performance, serum characteristics and meat quality of growing pigs. J Anim Physiol Anim Nutr (Berl). 2023;107(4).(2023)1111/jpn.13804.: 1035.
    10.1111/jpn.13804
    Article|CAS|PubMed|Google Scholar
  93. 93.Su WF, Jiang ZP, Wang C, Xu BC, Lu ZQ, Wang FQ, et al. Dynamics of defatted rice bran in physicochemical characteristics, microbiota and metabolic functions during two-stage co-fermentation. Int J Food Microbiol. 2022;362.(2022)2021.109489.: 109489.
    10.1016/j.ijfoodmicro.2021.109489
    Article|CAS|PubMed|Google Scholar
  94. 94.Wang C, Shi CY, Su WF, Jin ML, Xu Bc, Hao LH, et al. Dynamics of the physicochemical characteristics, microbiota, and metabolic functions of soybean meal and corn mixed substrates during two-stage solid-state fermentation. mSystems. 2020.https.(2020)1128/mSystems.00501-19.
    10.1128/mSystems.00501-19
    Article|CAS|PubMed|Google Scholar
  95. 95.Zheng L, Li D, Li ZL, Kang LN, Jiang YY, Liu XY, et al. Effects ofBacillusfermentation on the protein microstructure and anti-nutritional factors of soybean meal. Lett Appl Microbiol. 2017;65(6).(2017)1111/lam.12806.: 520.
    10.1111/lam.12806
    Article|CAS|PubMed|Google Scholar
  96. 96.Olukomaiya OO, Fernando WC, Mereddy R, Li X, Sultanbawa Y. Solid-state fermentation of canola meal withAspergillus sojae,Aspergillus ficuumand their co-cultures.(2020)effects on physicochemical, microbiological and functional properties.LWT.
    10.1016/j.lwt.2020.109362
    Article|CAS|PubMed|Google Scholar
  97. 97.Shi CY, He J, Yu J, Yu B, Huang ZQ, Mao XB, et al. Solid state fermentation of rapeseed cake withAspergillus nigerfor degrading glucosinolates and upgrading nutritional value. J Anim Sci Biotechnol. 2015;6.(2015)org/10.1186/s40104-015-0015-2.: 13.
    10.1186/s40104-015-0015-2
    Article|CAS|PubMed|Google Scholar
  98. 98.Mukherjee R, Chakraborty R, Dutta A. Role of fermentation in improving nutritional quality of soybean meal - A Review. Asian Austral J Anim. 2016;29(11).(2016)15.0627.: 1523.
    10.5713/ajas.15.0627
    Article|CAS|PubMed|Google Scholar
  99. 99.Mok WK, Tan YX, Lee J, Kim J, Chen WN. A metabolomic approach to understand the solid-state fermentation of okara usingBacillus subtilisWX-17 for enhanced nutritional profile. AMB Express. 2019;9(1).(2019)org/10.1186/s13568-019-0786-5.: 60.
    10.1186/s13568-019-0786-5
    Article|CAS|PubMed|Google Scholar
  100. 100.Feng HY, Qu H, Liu Y, Shi YH, Wu SL, Bao WB. Effect of fermented soybean meal supplementation on some growth performance, blood chemical parameters, and fecal microflora of finishing pigs. Rev Bras Zootec. 2020.https.(2020)org/10.37496/rbz4920190096.
    10.37496/rbz4920190096
    Article|CAS|PubMed|Google Scholar
  101. 101.Song J, Wang X, Cao Y, He Y, Yang Y. Effects of corn-soybean meal-based fermented feed supplementation on growth performance, meat quality, fatty acid profiles, nutritional values, and gut microbiota of lean-type finishing pigs. Foods. 2025;14(15).(2025)org/10.3390/foods14152641.: 2641.
    10.3390/foods14152641
    Article|CAS|PubMed|Google Scholar
  102. 102.Han G, Liu S, Zhao C, Lei L, Yi R, Ma Z, et al. Effects of fermented liquid feed on growth performance, meat quality, and intestinal microbiota of Yuedong Black Pigs. Animals. 2025;15(18).(2025)org/10.3390/ani15182657.: 2657.
    10.3390/ani15182657
    Article|CAS|PubMed|Google Scholar
  103. 103.Zhang A, Zheng Y, Yin W, Pu X, Yu A, Wang H, et al. Impact of fermented liquid feed supplementation on grower-fattening pigs production.(2025)insights into growth performance, carcass traits, meat quality, and metabolite profiles.Food Chem Mol Sci.: 100268.
    10.1016/j.fochms.2025.100268
    Article|CAS|PubMed|Google Scholar
  104. 104.Ma W, Ma Z, Mao P, Zhang X, Wu X, Gao M, et al. Effects of feed supplemented with fermented pine needles (Pinus ponderosa) on carcass quality, meat quality, and antioxidant capacity of growing-finishing pigs. Foods. 2025;14(12).(2025)org/10.3390/foods14122046.: 2046.
    10.3390/foods14122046
    Article|CAS|PubMed|Google Scholar
  105. 105.Li XY, Zhang L, Zhang YM, Luo X, Yu J, Ren SF, et al. Effects of dietaryInonotus obliquusfermentation products supplementation on meat quality and antioxidant capacity of finishing pigs. Meat Sci. 2025;224.(2025)109789. https://doi. org/10. 1016/j.meatsci.: 109789.
    10.1016/j.meatsci.2025.109789
    Article|CAS|PubMed|Google Scholar
  106. 106.Zhao ZW, Wu J, Yao XH, Sun H, Wu YF, Zhou HH, et al. Influence of fermented broccoli residues on fattening performance, nutrient utilization, and meat properties of finishing pigs. Animals. 2024.https.(2024)org/10.3390/ani14131987.
    10.3390/ani14131987
    Article|CAS|PubMed|Google Scholar
  107. 107.Niu JK, Liu X, Xu JY, Li F, Wang JC, Zhang XX, et al. Effects of silage diet on meat quality through shaping gut microbiota in finishing pigs. Microbiol Spectr. 2023;11(1).(2023)1128/spectrum.02416-22.
    10.1128/spectrum.02416-22
    Article|CAS|PubMed|Google Scholar
  108. 108.Chaiwang N, Bunmee T, Arjin C, Wattanakul W, Krutthai N, Mekchay S, et al. Effect of deep bedding floor and fermented feed supplement on productive performance, carcase, meat quality and fatty acid profile of crossbred pigs. Ital J Anim Sci. 2021;20(1).(2021)479–88. https://doi. org/10.1080/1828051x.: 479.
    10.1080/1828051x.2021.1893133
    Article|CAS|PubMed|Google Scholar
  109. 109.Fang JC, Cao Y, Matsuzaki M, Suzuki H, Kimura H. Effects of apple pomace-mixed silage on growth performance and meat quality in finishing pigs. Anim Sci J. 2016;87(12).(2016)1111/asj.12601.: 1516.
    10.1111/asj.12601
    Article|CAS|PubMed|Google Scholar
  110. 110.Chu GM, Kang SN, Nam JM, Kim HY, Ha JH, Ibrahim RIH, et al. Effects of dietary fermented persimmon diet on the meat quality of fattening pigs. Korean J Food Sci Anim Resour. 2012;32(5).(2012)604–11. https://doi. org/10.5851/kosfa.: 604.
    10.5851/kosfa.2012.32.5.604
    Article|CAS|PubMed|Google Scholar
  111. 111.Chu GM, Kang SN, Yang JM, Kim HY, Song YM. Effects of a dietary fermented mushroom (Flammulina velutipes) by-product diet on pork meat quality in growing-fattening Berkshire pigs. J Anim Sci Technol. 2012;54(3).(2012)199–207. https://doi. org/10.5187/jast.: 199.
    10.5187/jast.2012.54.3.199
    Article|CAS|PubMed|Google Scholar
  112. 112.Yan L, Kim IH. Effect of dietary grape pomace fermented bySaccharomyces boulardIIon the growth performance, nutrient digestibility and meat quality in finishing pigs. Asian Austral J Anim. 2011;24(12).(2011)1763–70. https://doi. org/10.5713/ajas.: 1763.
    10.5713/ajas.2011.11189
    Article|CAS|PubMed|Google Scholar
  113. 113.Yan L, Meng QW, Kim IH. Effects of fermented garlic powder supplementation on growth performance, nutrient digestibility, blood characteristics and meat quality in growing-finishing pigs. Anim Sci J. 2011;83(5).(2011)411–7. https://doi. org/10. 1111/j.1740-0929.: 411.
    10.1111/j.1740-0929.2011.00973.x
    Article|CAS|PubMed|Google Scholar
  114. 114.Ao X, Meng QW, Kim IH. Effects of fermented red ginseng supplementation on growth performance, apparent nutrient digestibility, blood hematology and meat quality in finishing pigs. Asian-Australas J Anim Sci. 2011;24(4).(2011)525–31. https://doi. org/10.5713/ajas.: 525.
    10.5713/ajas.2011.10397
    Article|CAS|PubMed|Google Scholar
  115. 115.Lee SD, Kim HY, Jung HJ, Ji SY, Chowdappa R, Ha JH, et al. The effect of fermented apple diet supplementation on the growth performance and meat quality in finishing pigs. Anim Sci J. 2009;80(1).(2009)00598.x.: 79.
    10.1111/j.1740-0929.2008.00598.x
    Article|CAS|PubMed|Google Scholar
  116. 116.Sasaki K, Nishioka T, Ishizuka Y, Saeki M, Kawashima T, Irie M, et al. Comparison of sensory traits and preferences between food co-product fermented liquid (FCFL)-fed and formula-fed pork loin. Asian-Australas J Anim Sci. 2007;20(8).(2007)1272–7. https://doi. org/10.5713/ajas.: 1272.
    10.5713/ajas.2007.1272
    Article|CAS|PubMed|Google Scholar
  117. 117.Song YM, Lee SD, Chowdappa R, Kim HY, Jin SK, Kim IS. Effects of fermented oyster mushroom (Pleurotus ostreats) by-product supplementation on growth performance, blood parameters and meat quality in finishing Berkshire pigs. Animal. 2007;1(2).(2007)org/10.1017/S1751731107683785.: 301.
    10.1017/S1751731107683785
    Article|CAS|PubMed|Google Scholar
  118. 118.Tang XP, Liu XG, Zhang K. Effects of microbial fermented feed on serum biochemical profile, carcass traits, meat amino acid and fatty acid profile, and gut microbiome composition of finishing pigs. Front Vet Sci. 2021;8.(2021)744630. https://doi. org/10.3389/fvets.: 744630.
    10.3389/fvets.2021.744630
    Article|CAS|PubMed|Google Scholar
  119. 119.Mancini RA, Hunt MC. Current research in meat color. Meat Sci. 2005;71(1).(2005)100–21. https://doi. org/10. 1016/j.meatsci.: 100.
    10.1016/j.meatsci.2005.03.003
    Article|CAS|PubMed|Google Scholar
  120. 120.Viljoen HF, de Kock HL, Webb EC. Consumer acceptability of dark, firm and dry (DFD) and normal pH beef steaks. Meat Sci. 2002;61(2).(2002)org/10.1016/s0309-1740(01)00183-8.: 181.
    10.1016/s0309-1740(01)00183-8
    Article|CAS|PubMed|Google Scholar
  121. 121.Zdunczyk W, Tkacz K, Modzelewska-Kapitula M. The effect of superficial oregano essential oil application on the quality of modified atmosphere-packed pork loin. Foods. 2023;12(10).(2023)org/10.3390/foods12102013.: 2013.
    Article|CAS|PubMed|Google Scholar
  122. 122.Lindahl G, Lundstrom K, Tornberg E. Contribution of pigment content, myoglobin forms and internal reflectance to the colour of pork loin and ham from pure breed pigs. Meat Sci. 2001;59(2).(2001)org/10.1016/s0309-1740(01)00064-x.: 141.
    10.1016/s0309-1740(01)00064-x
    Article|CAS|PubMed|Google Scholar
  123. 123.Hughes J, Clarke F, Li Y, Purslow P, Warner R. Differences in light scattering between pale and dark beef longissimus thoracis muscles are primarily caused by differences in the myofilament lattice, myofibril and muscle fibre transverse spacings. Meat Sci. 2019;149.(2019)11.006.: 96.
    10.1016/j.meatsci.2018.11.006
    Article|CAS|PubMed|Google Scholar
  124. 124.Hughes J, Clarke F, Purslow P, Warner R. High pH in beef longissimus thoracis reduces muscle fibre transverse shrinkage and light scattering which contributes to the dark colour. Food Res Int. 2017;101.(2017)228–38. https://doi. org/10. 1016/j.foodres.: 228.
    10.1016/j.foodres.2017.09.003
    Article|CAS|PubMed|Google Scholar
  125. 125.Moeller SJ, Miller RK, Edwards KK, Zerby HN, Logan KE, Aldredge TL, et al. Consumer perceptions of pork eating quality as affected by pork quality attributes and end-point cooked temperature. Meat Sci. 2010;84(1).(2010)06.023.: 14.
    10.1016/j.meatsci.2009.06.023
    Article|CAS|PubMed|Google Scholar
  126. 126.Liu SQ, Tu YA, Sun JB, Cai PR, Zhou YB, Huang YQ, et al. Fermented mixed feed regulates intestinal microbial community and metabolism and alters pork flavor and umami. Meat Sci. 2023.https.(2023)//doi. org/10. 1016/j.meatsci.
    10.1016/j.meatsci.2023.109177
    Article|CAS|PubMed|Google Scholar
  127. 127.Frank D, Joo ST, Warner R. Consumer acceptability of intramuscular fat. Korean J Food Sci Anim Resour. 2016;36(6).(2016)699–708. https://doi. org/10.5851/kosfa.: 699.
    10.5851/kosfa.2016.36.6.699
    Article|CAS|PubMed|Google Scholar
  128. 128.Hocquette JF, Gondret F, Baeza E, Medale F, Jurie C, Pethick DW. Intramuscular fat content in meat-producing animals.(2010)development, genetic and nutritional control, and identification of putative markers.Animal.: 303.
    10.1017/S1751731109991091
    Article|CAS|PubMed|Google Scholar
  129. 129.Fortin A, Robertson WM, Tong AKW. The eating quality of Canadian pork and its relationship with intramuscular fat. Meat Sci. 2005;69(2).(2005)07.011.: 297.
    10.1016/j.meatsci.2004.07.011
    Article|CAS|PubMed|Google Scholar
  130. 130.Fernandez X, Monin G, Talmant A, Mourot J, Lebret B. Influence of intramuscular fat content on the quality of pig meat - 2. Consumer acceptability ofm. longissimus lumborum. Meat Sci. 1999;53(1).(1999)org/10.1016/s0309-1740(99)00038-8.: 67.
    10.1016/s0309-1740(99)00038-8
    Article|CAS|PubMed|Google Scholar
  131. 131.Font-i-Furnols M, Tous N, Esteve-Garcia E, Gispert M. Do all the consumers accept marbling in the same way? The relationship between eating and visual acceptability of pork with different intramuscular fat content. Meat Sci. 2012;91(4).(2012)448–53. https://doi. org/10. 1016/j.meatsci.: 448.
    10.1016/j.meatsci.2012.02.030
    Article|CAS|PubMed|Google Scholar
  132. 132.Hou JJ, Ji X, Chu XR, Shi ZY, Wang BJ, Sun KL, et al. Comprehensive lipidomic analysis revealed the effects of fermentedMorus albaL. intake on lipid profile in backfat and muscle tissue of Yuxi black pigs. J Anim Physiol Anim Nutr (Berl). 2024;108(3).(2024)1111/jpn.13932.: 764.
    10.1111/jpn.13932
    Article|CAS|PubMed|Google Scholar
  133. 133.Lenighan YM, McNulty BA, Roche HM. Dietary fat composition.(2019)replacement of saturated fatty acids with PUFA as a public health strategy, with an emphasis on α-linolenic acid.Proc Nutr Soc.: 234.
    10.1017/s0029665118002793
    Article|CAS|PubMed|Google Scholar
  134. 134.Tortosa-Caparrós E, Navas-Carrillo D, Marín F, Orenes-Piñero E. Anti-inflammatory effects of omega 3 and omega 6 polyunsaturated fatty acids in cardiovascular disease and metabolic syndrome. Crit Rev Food Sci Nutr. 2017;57(16).(2017)2015.1126549.: 3421.
    10.1080/10408398.2015.1126549
    Article|CAS|PubMed|Google Scholar
  135. 135.Wood JD, Richardson RI, Nute GR, Fisher AV, Campo MM, Kasapidou E, et al. Effects of fatty acids on meat quality.(2004)a review.Meat Sci.: 21.
    10.1016/S0309-1740(03)00022-6
    Article|CAS|PubMed|Google Scholar
  136. 136.Yi WZ, Huang QX, Wang YZ, Shan TZ. Lipo-nutritional quality of pork.(2023)the lipid composition, regulation, and molecular mechanisms of fatty acid deposition.Anim Nutr.: 373.
    10.1016/j.aninu.2023.03.001
    Article|CAS|PubMed|Google Scholar
  137. 137.Frayn KN, Arner P, Yki-Jarvinen H. Fatty acid metabolism in adipose tissue, muscle and liver in health and disease. Essays Biochem. 2006;42.(2006)org/10.1042/bse0420089.: 89.
    10.1042/bse0420089
    Article|CAS|PubMed|Google Scholar
  138. 138.Zhang ZQ, Zang MW, Zhang KH, Wang SW, Li D, Li XM. Effects of phospholipids and reheating treatment on volatile compounds in phospholipid-xylose-cysteine reaction systems. Food Res Int. 2021;139.(2021)2020.109918.: 109918.
    10.1016/j.foodres.2020.109918
    Article|CAS|PubMed|Google Scholar
  139. 139.Liu SQ, Du M, Sun JB, Tu YA, Gu X, Cai PR, et al.Bacillus subtilisandEnterococcus faeciumco-fermented feed alters antioxidant capacity, muscle fibre characteristics and lipid profiles of finishing pigs. Br J Nutr. 2024;131(8).(2024)org/10.1017/S000711452300291X.: 1298.
    10.1017/S000711452300291X
    Article|CAS|PubMed|Google Scholar
  140. 140.Shi M, Yang YN, Hu XS, Zhang ZY. Effect of ultrasonic extraction conditions on antioxidative and immunomodulatory activities of aGanoderma lucidumpolysaccharide originated from fermented soybean curd residue. Food Chem. 2014;155.(2014)50–6. https://doi. org/10. 1016/j.foodchem.: 50.
    10.1016/j.foodchem.2014.01.037
    Article|CAS|PubMed|Google Scholar
  141. 141.Akbari M, Razavi SH, Khodaiyan F, Blesa J, Esteve MJ. Fermented corn bran.(2023)a by-product with improved total phenolic content and antioxidant activity.LWT.
    10.1016/j.lwt.2023.115090
    Article|CAS|PubMed|Google Scholar
  142. 142.Sawangwan T, Porncharoennop C, Nimraksa H. Antioxidant compounds from rice bran fermentation by lactic acid bacteria. AIMS Agric Food. 2021;6(2).(2021)578–87. https://doi. org/10.3934/agrfood.: 578.
    10.3934/agrfood.2021034
    Article|CAS|PubMed|Google Scholar
  143. 143.Meng QW, Yan L, Ao X, Zhou TX, Wang JP, Lee JH, et al. Influence of probiotics in different energy and nutrient density diets on growth performance, nutrient digestibility, meat quality, and blood characteristics in growing-finishing pigs. J Anim Sci. 2010;88(10).(2010)2527/jas.2009-2308.: 3320.
    10.2527/jas.2009-2308
    Article|CAS|PubMed|Google Scholar
  144. 144.Xie CL, Teng JY, Wang XK, Xu BY, Niu YR, Ma LB, et al. Multi-omics analysis reveals gut microbiota-induced intramuscular fat deposition via regulating expression of lipogenesis-associated genes. Anim Nutr. 2022;9.(2022)10.010.: 84.
    10.1016/j.aninu.2021.10.010
    Article|CAS|PubMed|Google Scholar
  145. 145.Xie CL, Zhu XY, Xu BY, Niu YR, Zhang XL, Ma LB, et al. Integrated analysis of multi-tissues lipidome and gut microbiome reveals microbiota-induced shifts on lipid metabolism in pigs. Anim Nutr. 2022;10.(2022)280–93. https://doi. org/10. 1016/j.aninu.: 280.
    10.1016/j.aninu.2022.04.011
    Article|CAS|PubMed|Google Scholar
  146. 146.Fang SM, Xiong XW, Su Y, Huang LS, Chen CY. 16S rRNA gene-based association study identified microbial taxa associated with pork intramuscular fat content in feces and cecum lumen. BMC Microbiol. 2017;17.(2017)org/10.1186/s12866-017-1055-x.: 162.
    10.1186/s12866-017-1055-x
    Article|CAS|PubMed|Google Scholar
  147. 147.You WJ, Liu SQ, Ji JF, Ling DF, Tu YA, Zhou YB, et al. Growth arrest and DNA damage-inducible alpha regulates muscle repair and fat infiltration through ATP synthase F1 subunit alpha. J Cachexia Sarcopenia Muscle. 2023;14(1).(2023)1002/jcsm.13134.: 326.
    10.1002/jcsm.13134
    Article|CAS|PubMed|Google Scholar
  148. 148.You WJ, Xu ZY, Sun Y, Valencak TG, Wang YZ, Shan TZ. GADD45α drives brown adipose tissue formation through upregulating PPARgamma in mice. Cell Death Dis. 2020;11(7).(2020)org/10.1038/s41419-020-02802-5.: 585.
    Article|CAS|PubMed|Google Scholar
  149. 149.Duan YH, Li FN, Wang WL, Guo QP, Wen CY, Yin YL. Alteration of muscle fiber characteristics and the AMPK-SIRT1-PGC-1α axis in skeletal muscle of growing pigs fed low-protein diets with varying branched-chain amino acid ratios. Oncotarget. 2017;8(63).(2017)18632/oncotarget.22205.: 107011.
    10.18632/oncotarget.22205
    Article|CAS|PubMed|Google Scholar
  150. 150.Choi YM, Ryu YC, Kim BC. Influence of myosin heavy- and light chain isoforms on early postmortem glycolytic rate and pork quality. Meat Sci. 2007;76(2).(2007)11.009.: 281.
    10.1016/j.meatsci.2006.11.009
    Article|CAS|PubMed|Google Scholar
  151. 151.Li BJ, Yin D, Li PH, Zhang ZK, Zhang XY, Li HQ, et al. Profiling and functional analysis of circular RNAs in porcine fast and slow muscles. Front Cell Dev Biol. 2020;8.(2020)322. https://doi. org/10.3389/fcell.: 322.
    10.3389/fcell.2020.00322
    Article|CAS|PubMed|Google Scholar
  152. 152.Hwang YH, Kim GD, Jeong JY, Hur SJ, Joo ST. The relationship between muscle fiber characteristics and meat quality traits of highly marbled Hanwoo (Korean native cattle) steers. Meat Sci. 2010;86(2).(2010)456–61. https://doi. org/10. 1016/j.meatsci.: 456.
    10.1016/j.meatsci.2010.05.034
    Article|CAS|PubMed|Google Scholar
  153. 153.Luo YL, Ju N, Chang J, Ge RX, Zhao YY, Zhang GJ. Dietary alpha-lipoic acid supplementation improves postmortem color stability of the lamb muscles through changing muscle fiber types and antioxidative status. Meat Sci. 2022;193.(2022)108945. https://doi. org/10. 1016/j.meatsci.: 108945.
    10.1016/j.meatsci.2022.108945
    Article|CAS|PubMed|Google Scholar
  154. 154.Mizunoya W, Iwamoto Y, Shirouchi B, Sato M, Komiya Y, Razin FR, et al. Dietary fat influences the expression of contractile and metabolic genes in rat skeletal muscle. PLoS ONE. 2013;8(11).(2013)pone.0080152.
    10.1371/journal.pone.0080152
    Article|CAS|PubMed|Google Scholar
  155. 155.Nakazato K, Song H. Increased oxidative properties of gastrocnemius in rats fed on a high-protein diet. J Nutr Biochem. 2008;19(1).(2008)12.019.: 26.
    10.1016/j.jnutbio.2006.12.019
    Article|CAS|PubMed|Google Scholar
  156. 156.Zhang WG, Xiao S, Ahn DU. Protein oxidation.(2013)basic principles and implications for meat quality.Crit Rev Food Sci Nutr.: 1191.
    10.1080/10408398.2011.577540
    Article|CAS|PubMed|Google Scholar
  157. 157.Chen J, Tian M, Guan W, Wen T, Yang F, Chen F, et al. Increasing selenium supplementation to a moderately-reduced energy and protein diet improves antioxidant status and meat quality without affecting growth performance in finishing pigs. J Trace Elem Med Biol. 2019;56.(2019)38–45. https://doi. org/10. 1016/j.jtemb.: 38.
    10.1016/j.jtemb.2019.07.004
    Article|CAS|PubMed|Google Scholar
  158. 158.Simonetti A, Perna A, Gambacorta E. Comparison of antioxidant compounds in pig meat from Italian autochthonous pig Suino Nero Lucano and a modern crossbred pig before and after cooking. Food Chem. 2019;292.(2019)108–12. https://doi. org/10. 1016/j.foodchem.: 108.
    10.1016/j.foodchem.2019.04.057
    Article|CAS|PubMed|Google Scholar

Acknowledgements

Not applicable.

Funding

We thank members of the Shan Laboratory for comments and this work was partially supported by the National Natural Science Foundation of China (32272887), the Natural Science Foundation of Zhejiang Province (LZ22C170003) to TZS.

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Competing interests

The authors declare no competing interests.

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