Animal MicrobiomeandJournal of Animal Science and Biotechnologycall for submissions to the collection on Animal Gut Nutrition and Greenhouse Gas Mitigation. Efforts to reduce greenhouse gas emissions from livestock systems increasingly hinge on innovations in animal gut nutrition. The dynamic relationship between the gut microbiome and nutrient utilization plays a pivotal role in shaping methane output, feed efficiency, and overall sustainability. Advances in microbial ecology—particularly in understanding the role of gut microbiome in nutrient metabolism—are opening new pathways for mitigating emissions while enhancing productivity. These developments support the implementation of climate-smart agricultural strategies to address climate change and its impacts. Looking ahead, continued research in this field has the potential to yield innovative solutions such as targeted probiotic supplementation, which could further optimize gut function and enhance nutrient absorption. These advancements may lead to reduced greenhouse gas emissions while improving animal health and productivity. By deepening our understanding of the animal gut microbiome, we can contribute significantly to sustainable agricultural practices that benefit both the environment and food security. We invite researchers to contribute to this special Collection on Animal Gut Nutrition and Greenhouse Gas Mitigation. Topics of interest include but are not limited to: All submissions in this collection undergo the relevant journal’s standard peer review process. Similarly, all manuscripts authored by a Guest Editor(s) will be handled by the Editor-in-Chief of the relevant journal. As an open access publication, participating journals levy an article processing fee (Animal Microbiomefees,Journal of Animal Science and Biotechnologyfees). We recognize that many key stakeholders may not have access to such resources and are committed to supporting participation in this issue wherever resources are a barrier. For more information about what support may be available, please visitOA funding and support, or emailOAfundingpolicy@springernature.comor the Editor-in-Chief of the journal where the article is being submitted. Submit your manuscript to this collection through a participating journal. Journal of Animal Science and Biotechnology is a leading open access journal publishing innovative research across agriculture, dairy and animal science. Animal Microbiome is a community-focused journal welcoming all animal microbiome studies relating to domestic and non-domestic animals.